MAKING GENOMICS WORK
AT THE POINT OF CARE
What is CDSS?
Clinical Decision Support System (CDSS)
The Clinical Decision Support System (CDSS) at Precision Diagnostics is a proprietary digital interface designed to bridge the gap between complex genomic data and real-time clinical decision-making. Integrated into PRECISE Doctor Portal and compatible with leading PRECISE Electronic Health Record (PreciseEHR) systems, it empowers healthcare professionals to make accurate, timely, and personalised therapeutic choices.
The reason behind
Why CDSS Matters
Clinical decisions based on traditional protocols do not account for genetic variability, which may lead to adverse drug reactions, ineffective treatments, and avoidable hospital readmissions.
A 2022 study by Keogh, Fragala, and colleagues revealed that “DNA testing, a clinical decision support system, and pharmacists were used together to identify medication safety and effectiveness issues and recommend appropriate changes.” This highlights the essential role of CDSS in interpreting pharmacogenomic data and supporting safer, evidence-based prescribing.
key features
Core Capabilities
Genotype-to-Drug Alerts
Instantly flags when a prescribed drug may be ineffective or dangerous based on the patient's genetic profile
Alternative Drug Recommendations
Suggests alternative medications with safer or more effective pharmacogenomic profiles
Dose Optimization Engine
Suggests alternative medications with safer or more effective pharmacogenomic profiles
Nutrigenomics Recommendations
Offers diet and supplement advice for patients with NGx testing to manage chronic conditions or enhance wellness
Context-Aware Decision Trees
Considers polypharmacy, age, gender, renal and hepatic status to support complex prescribing scenarios
implementation
Integrated Workflow
EHR Integration
Enables clinicians to access PGx & NGx results via the PRECISE Doctor Portal, while patients can view their results in real time through the PreciseEHR Mobile App.
Secured Mobile Alerts
Patients and clinicians receive alerts for high-risk prescriptions in real time.
Documentation Support
Provides structured clinical summaries and risk insights that clinicians can reference or manually include in their patient records.
Compliance Alignment
Conforms with CPIC, FDA boxed warnings, and HSA standards.
By embedding the CDSS into every clinical interaction, we turn data into decisions and genetics into genuine health outcomes. We do this reliably, securely, and intelligently.
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Source: Keogh M, Fragala MS, Peter AP, Lorenz RA, Goldberg SE, Shaman JA. Early Insights From a Pharmacogenomic-Enriched Comprehensive Medication Management Program Implementation in an Adult Employee Population. J Occup Environ Med. 2022 Dec 1;64(12):e818-e822. doi: 10.1097/JOM.0000000000002705. Epub 2022 Sep 22. PMID: 36155954; PMCID: PMC9722373.