MAKING GENOMICS WORK
AT THE POINT OF CARE
What is CDSS?
Clinical Decision Support System (CDSS)
The Clinical Decision Support System (CDSS) at Precision Diagnostics is a proprietary digital interface designed to bridge the gap between complex genomic data and real-time clinical decision-making. Integrated into our Clinical Accredited Reports, Doctor Portal, Electronic Health Record (PreciseEHR) systems, and Electronic Medical Record (EMR), it empowers healthcare professionals to make accurate, timely, and personalised therapeutic choices.
The reason behind
Why PRECISE-CDSS Matters
Clinical decisions based on traditional protocols do not account for genetic variability, which may lead to adverse drug reactions, ineffective treatments, and unnecessary hospital readmissions.
A 2022 study by Keogh, Fragala, and colleagues revealed that “DNA testing, a clinical decision support system, and pharmacists were used together to identify medication safety and effectiveness issues and recommend appropriate changes.” This highlights the essential role of PRECISE-CDSS in interpreting pharmacogenomics data and supporting safer, evidence-based prescribing.
key features
Core Capabilities
Guideline Integration and Knowledge Base
Integrates trusted pharmacogenomic guidelines such as CPIC, FDA, DPWG, IWPC or drug label recommendations, enabling evidence-based alerts and recommendations.
Genotype-to-Drug Interpretation Module
Automatically translates raw genetic test results (e.g., CYP2C19 *2/*3) into clinically meaningful phenotypes (e.g., poor metabolizer), ensuring accurate interpretation for decision-making.
Clinical Actionable for Alternative Drug Recommendations
Suggests alternative medications with safer or more effective pharmacogenomic profiles
Clinical Actionable for Dose Optimization
Provides evidence-based dosage adjustments, reducing the risk of over- or under-dosing.
Clinician-Friendly Interface
Includes brief clinical evidence explanations and guideline references within alerts to help clinicians understand the pharmacogenomic rationale behind each recommendation.
Patient-Centric View
Delivers easy-to-understand summaries for patients that increase confidence and adherence to genetic-guided treatments provided by healthcare providers.
Preemptive Decision Support
Stores and reuses genetic information for future prescriptions, providing proactive alerts even before an adverse event or new order occurs.
Data Security and Privacy Framework
Implements robust access control and encryption to protect sensitive genetic and health data, complying with regulations like PDPA.
By embedding the PRECISE-CDSS into every clinical interaction, we turn data into informed decisions and genetics into genuine health outcomes. We do this reliably, securely, and intelligently.
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Source: Keogh M, Fragala MS, Peter AP, Lorenz RA, Goldberg SE, Shaman JA. Early Insights From a Pharmacogenomic-Enriched Comprehensive Medication Management Program Implementation in an Adult Employee Population. J Occup Environ Med. 2022 Dec 1;64(12):e818-e822. doi: 10.1097/JOM.0000000000002705. Epub 2022 Sep 22. PMID: 36155954; PMCID: PMC9722373.