Why Medication Safety Needs Personalisation

Every person’s genes are unique. Understanding yours helps clinicians select the most appropriate medication and dose, supporting better outcomes and improved medication safety.

4ᵗʰ - 6ᵗʰ

Adverse Drug Reactions (ADRs) are the 4ᵗʰ - 6ᵗʰ leading cause of death worldwide ¹ ².

> 50%

of patients are non-adherent to treatment, due to adverse effects or lack of effectiveness ³.

52%

of outpatient drug-related complications could have been avoided ⁴.

Trust The Science

Pharmacogenomics offers the potential to ensure that individuals only take medications with no or minimal side effects and optimal effectiveness for them. Did you know;

80%

Pharmacogenomics is responsible for ~ 80% variability in genes associated with drug safety and efficacy ⁵.

~ 30%

reduction in Adverse Drug Reactions (ADRs) cases with pharmacogenomic-guided prescription ⁶.

~ 70%

of Physicians opted to modify drug or dosage using Pharmacogenomics testing to reduce Adverse Drug Reactions (ADRs) ⁶.

BASED ON TRUE STORY FROM THE LANCET

A TRAGIC LOSS THAT COULD HAVE BEEN PREVENTED

A 13-day-old infant tragically passed away from morphine poisoning after the mother, unknowingly a CYP2D6 ultra-rapid metabolizer, took a common codeine-based painkiller. Her body converted codeine into dangerously high morphine levels, ~30X higher than normal, which were then passed to her baby through breast milk.

This heartbreaking case — reported in The Lancet — highlights the urgent need for pharmacogenomic testing. If the mother had known her genetic profile, she could have avoided codeine and chosen a safer pain relief option — potentially saving her baby’s life.

Unlock Your Health With Precise DNA Tests

At Precision Diagnostics, we offer advanced genetic profiling to provide personalized health strategies based on your unique DNA. Our reports are grounded in the latest scientific research and globally accepted clinical guidelines. Every recommendation is aligned with trusted sources, ensuring you receive clinically actionable insights that evolve with modern medicine.

PRECISE Pharmacogenomics:
Smarter Medications, Better Outcomes

• Personalized medication plans
• Reduced side effects
• Faster, more effective treatments
• Smarter spending with fewer ineffective treatments

PRECISE Nutrigenomics:
Nutrition Tailored to You

• Customized diet and supplement plans
• Disease prevention
• Weight management
• Enhanced sport performance

PRECISE ONCO+:
Personalised Cancer Treatment Starts Here

• Targeted drug selection
• Reduced toxicity
• Improved treatment outcome
• Data-driven guidance for treatment planning

Trusted By

We are honoured to work alongside esteemed organisations across education, healthcare, and wellness. These valued collaborators support our efforts in research, professional training, and community outreach.

Our Board Of Advisors

Leading The Way In Pharmacogenomics Innovation

References:

  1. S. Food and Drug Administration. (2018, March 6). Preventable adverse drug reactions: A focus on drug interactions. U.S. Food and Drug Administration. https://www.fda.gov/drugs/drug-interactions-labeling/preventable-adverse-drug-reactions-focus-drug-interactions
  2. Montastruc, J.-L., Lafaurie, M., de Canecause, C., et al. (2021). Fatal adverse drug reactions: A worldwide perspective in the World Health Organization pharmacovigilance database. British Journal of Clinical Pharmacology, 87(11), 4334–4340. https://doi.org/10.1111/bcp.14855
  3. Brown MT, Bussell JK. Medication adherence: WHO cares?. Mayo Clinic Proceedings. 2011;86(4):304–314. doi:10.4065/mcp.2010.0575.
  4. Hakkarainen KM, Hedna K, Petzold M, Hägg S. Percentage of patients with preventable adverse drug reactions and preventability of adverse drug reactions – a meta-analysis. PLoS ONE. 2012;7(3):e33236. doi:10.1371/journal.pone.0033236.
  5. Cacabelos, R., Cacabelos, N., & Carril, J. C. (2019). The role of pharmacogenomics in adverse drug reactions. Expert Review of Clinical Pharmacology, 12(5), 407–442. https://doi.org/10.1080/17512433.2019.1601875
  6. Swen, J. J., van der Wouden, C. H., Manson, L. E., et al. (2023). A 12-gene pharmacogenetic panel to prevent adverse drug reactions: An open-label, multicentre, controlled, cluster-randomised crossover implementation study. The Lancet, 401(10374), 347–356. https://doi.org/10.1016/S0140-6736(23)00102-0
  7. Royal College of Physicians and British Pharmacological Society. Personalised prescribing: using pharmacogenomics to improve patient outcomes. Report of a working party. London: RCP and BPS, 2022