PRECISE PHARMACOGENOMICS (PGx)
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Dr. Lee Han Chung
Laboratory Director (Molecular Division)
BSc in Biotechnology, MSc in Medical Science, PhD in Neuroscience
Doctor Lee Han Chung is a Molecular and Cellular Biologist. He received his Bachelor of Science in Biotechnology from Universiti Putra Malaysia (UPM) in 2005. With a passion for science and medical research, he continued his journey. He joined a research team in the Pathology Department at Universiti Kebangsaan Malaysia (UKM) Medical Centre, where he obtained his Master’s degree in Medical Science. He studied the association of inherited mutations in the BRCA1 and BRCA2 genes with high-risk breast cancer patients, particularly in patients diagnosed with breast cancer at a younger age or with any familial history of breast and ovarian cancer.
By integrating genetic information identified during his research with the known prevalence of BRCA1 and BRCA2 mutation in Malaysian Breast Cancer patients thereby allowing for better management of cancer patients. oving forward, he joined the Medical Genetics Laboratory at UPM to pursue his PhD which focuses on the altered signaling pathway leading to an imbalance number of neurons and glial cells by using the brain of the mouse model with Down Syndrome (DS). With the research output, it may lead to therapeutics that can improve the quality of life of individuals with DS.
Before joining Precision Diagnostics, Dr Lee is one of the members responsible for setting up research laboratories in a few Private universities, in addition to being a regulatory affairs personnel in a pharmaceutical company as well. He was the instructor and application specialist for molecular biology techniques in a private university and a life-science company, respectively.
Dr Lee is well-trained in molecular experimental designs, Next-Generation Sequencing (NGS), quantitative PCR, and cell-based techniques. His current interest is using genetic testing to tailor medical treatments to individual patients with different disease conditions.
Professional Qualifications
- Laboratory Director (Molecular) at Global Precision Diagnostics
- Assistant Treasurer at Precision Medicine & Scientific Wellness (PMedS)
- Regulatory Affairs Manager at Solution Biologics
- Scientist at Pantai Premier Pathology
- Laboratory Officer at Xiamen University Malaysia
- Graduate Student, PhD at Universiti Putra Malaysia
- Field Application Specialist at ScienceVision
- The IBRO International Travel Grants Award for attending the 39th Annual Meeting of the Japan Neuroscience Society, Yokohama, Japan, associated with Universiti Putra Malaysia (UPM)
- The IBRO-APRC Associate School of Neuroscience Award (International) for attending the Associate School of Neuroscience at the Faculty of Medical Science & Graduate School, Naresuan University, Phitsanulok, Thailand, associated with Universiti Putra Malaysia (UPM)
Publications
A three-dimensional collagen construct to model lipopolysaccharide-induced activation of BV2 microglia,
Deciphering the secret role of Sox4 gene locus during mouse cerebral corticogenesis,
Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks,
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